Overview
- The Yankees became the first MLB team to open two games in a season with three consecutive home runs, achieving the feat against Baltimore's Kyle Gibson on April 29 after doing so against Milwaukee's Nestor Cortes on March 29.
- New York's lineup hit six solo home runs, including two from Ben Rice, as part of a 19-hit offensive outburst at Camden Yards.
- Carlos Rodón carried a perfect game into the sixth inning, finishing with six-plus innings of two-run ball and seven strikeouts for his third consecutive quality start.
- Baltimore's Kyle Gibson, making his season debut, allowed nine runs and 11 hits in just 3⅔ innings, continuing struggles for the Orioles' pitching staff, which now owns the league's worst ERA.
- Jazz Chisholm Jr. exited the game in the first inning with right flank discomfort and is scheduled for further evaluation upon the team's return to New York.