Overview
- At 150 minutes of moderate-to-vigorous activity per week, women had a 22% lower risk of coronary heart disease, compared with 17% for men.
- To reach roughly a 30% reduction, women accrued about 250 weekly minutes of activity, whereas men needed around 530 minutes.
- Among participants with existing coronary disease, men required about 1.7 times more activity than women to achieve comparable relative mortality risk reductions.
- The study analyzed wearable-accelerometer data from more than 85,000 UK Biobank participants with a median follow-up of about eight years, recording 3,764 incident events among roughly 80,000 initially disease-free individuals.
- Cardiology experts urged sex-tailored activity guidance and further sex-specific research, while noting the UK Biobank’s limited representativeness and the need for replication in more diverse cohorts.