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Wireless Ultrasound Implant Delivers AI-Guided Chronic Pain Relief in Rodent Trials

This flexible, self-adaptive device taps external ultrasound energy to power spinal cord stimulation tailored to individual pain signals.

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Overview

  • The implant receives energy via an external wearable ultrasound transmitter and converts it into electrical pulses through a piezoelectric element.
  • A ResNet-18 based neural network processes EEG signals to classify pain into three levels with 94.8% accuracy, enabling real-time adjustments to stimulation intensity.
  • Rodent trials showed significant reductions in pain responses to mechanical and thermal stimuli, and animals preferred environments where the system was active.
  • By eliminating implanted batteries and hardwired connections, the UIWI stimulator addresses high costs, surgical invasiveness and maintenance burdens of current spinal cord stimulators.
  • Researchers say future versions could be miniaturized for syringe-based implantation and managed via smartphone software.