Overview
- WHO logged 409,222 cases and 4,738 deaths from January 1 to August 17, 2025, across 31 countries facing active outbreaks.
- Compared with the same period in 2024, reported cases fell about 20% while deaths rose 46%, with the overall risk of further spread rated very high.
- The Eastern Mediterranean Region recorded the most cases, and the African Region reported the most deaths, with rural and flood-affected communities flagged as especially vulnerable.
- The Republic of Congo and Chad currently have the highest case fatality rates at 7.7% and 6.8%, and six countries exceed the 1% threshold.
- WHO urges stronger surveillance and case management, rapid WASH scale-up, vaccination campaigns, and cross-border coordination; cholera is treatable with oral rehydration, with IV fluids and antibiotics needed for severe illness.