Overview
- NB.1.8.1 was first detected on January 22, 2025, as a recombinant offshoot of XDV.1.5.1 and placed under the WHO’s TAG-VE risk assessment.
- By May 18, 518 NB.1.8.1 sequences from 22 countries made up 10.7% of global COVID-19 samples, with the fastest growth in the Western Pacific, Americas and Europe.
- The WHO assesses the public health risk as low and reports no evidence that NB.1.8.1 causes more severe illness than other circulating variants.
- Member states are urged to conduct neutralization tests to gauge antibody response and to monitor vaccine effectiveness and clinical severity indicators.
- Patients infected with NB.1.8.1 report typical COVID-19 symptoms alongside pronounced fatigue and gastrointestinal discomfort.