Overview

• WHO Alert 4/2025 identifies six Fentanilo HLB injectable lots contaminated with multidrug‑resistant Klebsiella pneumoniae and Ralstonia pickettii, after an initial link to lot 31202.
• Argentina’s regulator suspended Laboratorios Ramallo in February and in May banned all HLB Pharma products, with WHO urging continued vigilance because doses may still be in circulation.
• Regulatory actions broadened as INAME/ANMAT inhibited Rigecin and Rivero within the past four days and ordered market withdrawals for hospital solutions over suspected contamination.
• Investigators report at least 96 deaths linked to the outbreak, while courts review 122 clinical records as potential cases in the federal probe.
• HLB/Ramallo owner Ariel García Furfaro remains detained as indagatorias continue this week, and WHO asks health systems to strengthen supply‑chain surveillance and report detections immediately.