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WHO Launches First Clinical Trial for Sudan Ebola Vaccine in Uganda

The trial follows a recent Ebola outbreak in Kampala, with a 32-year-old healthcare worker as the first reported fatality.

  • The World Health Organization (WHO) has initiated a clinical trial for a vaccine targeting the Sudan strain of the Ebola virus in Uganda.
  • The trial was rapidly organized after a confirmed Ebola outbreak in Kampala, which has already resulted in the death of a 32-year-old nurse.
  • The vaccine trial includes three ring vaccination groups, initially targeting approximately 40 individuals who were in contact with the deceased nurse and their close contacts.
  • Currently, there are no approved vaccines for the Sudan strain of Ebola, though vaccines exist for the Zaïre strain, which caused past outbreaks.
  • Uganda has a history of Ebola outbreaks, with the deadliest involving the Sudan strain in 2000, resulting in 224 deaths out of 425 cases.
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