Overview

• President Donald Trump said pregnant patients should limit acetaminophen to cases deemed medically necessary and stated the FDA will notify physicians and update warnings.
• Trump also questioned routine infant immunization, urging delays to the newborn hepatitis B shot and proposing changes to vaccine scheduling, drawing immediate public‑health concern.
• The administration spotlighted leucovorin as a potential intervention as the FDA posted a notice approving a formulation for cerebral folate deficiency, though it is not an established autism treatment.
• The American College of Obstetricians and Gynecologists and maternal‑fetal specialists rejected a causal link and cautioned that untreated fever in pregnancy poses proven risks to mothers and fetuses.
• Evidence remains mixed, with a 2024 Swedish JAMA sibling study finding no causal link and a 2025 review noting associations without proving causation, while Tylenol maker Kenvue disputes the claim and prior U.S. lawsuits were dismissed with appeals pending.