Overview

• Under the agreement, Pfizer will provide Most-Favored-Nation pricing to Medicaid and set MFN benchmarks for new drugs introduced in the U.S., according to officials.
• TrumpRx is described as a government-run search portal that routes consumers to manufacturers’ direct-sales sites, with the White House citing example cuts of 40% to 85% on select medicines.
• The administration says the platform is targeting an early 2026 debut, with construction, insurance usage and other operational details still being finalized.
• The industry is mounting its own direct-sale efforts, including PhRMA’s AmericasMedicines.com and Bristol Myers Squibb’s more than 80% discount for cash-paying patients on its psoriasis drug Sotyktu.
• Experts say much of the initial savings may flow to Medicaid programs and the effect on privately insured patients is unclear, as the White House continues pressing other drugmakers with tariff threats.