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White House Poised to Link Prenatal Tylenol to Autism Risk, Promote Leucovorin in Oval Office Briefing

Major medical groups and Tylenol’s maker reject a causal tie and urge caution as the administration tees up findings before any peer‑reviewed report is released.

Overview

  • President Trump says an autism announcement will be made Monday, with plans for him to appear alongside HHS Secretary Robert F. Kennedy Jr. and CMS Administrator Mehmet Oz at the White House.
  • Officials are expected to caution against acetaminophen use early in pregnancy except to treat fever and to flag low maternal folate as another risk factor, according to reporting from multiple outlets.
  • Leucovorin (folinic acid) will be highlighted as a potential symptom‑reducing therapy for autism, with early trials cited as suggestive and the FDA reviewing possible language, but evidence remains preliminary.
  • Research on prenatal acetaminophen and autism is mixed, including a large 2024 Swedish sibling‑controlled study finding no causal link, while some reviews report associations that do not establish causation.
  • Kenvue and leading obstetrics groups say prudent acetaminophen use in pregnancy is considered safe and warn that untreated pain or fever carries risks, as NIH separately rolls out an autism data‑science initiative funding 13 research teams.