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White House Links Prenatal Tylenol to Autism, Pushes Leucovorin Evaluation

Leading medical groups plus the Tylenol maker dispute the claim, citing mixed research with guidance that considers acetaminophen appropriate in pregnancy when used as directed.

Overview

  • President Trump used a White House briefing to assert a link between maternal acetaminophen use and autism and urged pregnant patients to avoid Tylenol.
  • HHS Secretary Robert F. Kennedy Jr. promoted leucovorin as a therapy to study for autism and referenced an FDA notice citing small studies in children and adults.
  • The American College of Obstetricians and Gynecologists reiterated that acetaminophen remains the preferred pain reliever in pregnancy when used as directed.
  • Kenvue, the maker of Tylenol, rejected any causal link to autism and warned that discouraging use could leave pregnant patients with riskier alternatives or untreated fever and pain.
  • Researchers highlighted conflicting evidence, noting earlier associations in observational work and a 2024 sibling-controlled analysis that weakened an autism link; Trump also questioned newborn hepatitis B vaccination, in contrast to guidance to immunize at birth.