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Wheat Pan-Transcriptome Published, Revealing Hidden Functional Diversity Across Cultivars

Researchers say the atlas will help breeders develop higher-yield, climate-resilient wheat.

Overview

  • An international consortium reported the de novo–annotated wheat pan-transcriptome and expression atlas in Nature Communications on October 6, 2025.
  • The resource builds on chromosome-level assemblies from the International 10+ Wheat Genomes Project and integrates transcript isoform sequencing across multiple tissues.
  • Analyses identify cultivar-specific genes and regulatory networks, with conserved expression among many homeologs alongside shifts in subgenome expression bias between varieties.
  • The team reports pronounced variation in the prolamin superfamily and immune‑reactive proteins across cultivars using the new atlas.
  • Authors position the publicly available resource as a tool to speed breeding for yield gains and resilience to heat, drought, and poor soils without greater fertilizer use, supported by BBSRC-funded programs.