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last wk.

Weight-Loss Injections Show Sharp Rebound Eight Weeks After Ending Therapy

Experts warn that sustaining benefits will likely demand indefinite therapy despite rising costs.

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Wie viel man nach der Abnehmspritze zunimmt, hängt besonders von einem Faktor ab
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Overview

  • A global meta-analysis of 11 randomized trials found participants regained significant weight beginning around eight weeks after stopping drugs such as Ozempic, Wegovy and Mounjaro.
  • The review combined data from 1,574 treated patients and 893 controls across Orlistat, Naltrexone/Bupropion, Phentermine/Topiramate and GLP-1 receptor agonists.
  • Patients with the greatest initial weight loss experienced larger rebounds, even after joining lifestyle modification programs.
  • U.S. figures show two-thirds of self-paying patients discontinue GLP-1 therapies within a year, while monthly treatment costs reach several hundred euros.
  • Diabetologists including Stephan Martin argue obesity must be managed as a chronic condition with long-term pharmacotherapy to maintain weight control.