Overview

• BetMGM reports the most popular sides by tickets and dollars include Lions +2.5 and Colts -7.5, reflecting heavy public interest in those matchups.
• Chiefs–Lions on Sunday night sits around Kansas City -2.5, and traders cite balanced action with the total pushed up by bettors from roughly 49.5 to 52.5.
• SportsLine’s 10,000-simulation model highlights an Under lean on Chiefs–Lions (52.5), projecting about 51 points, and touts a long-term top-rated picks profit run.
• The largest Week 6 spread is Bengals at Packers near -14.5, with Joe Flacco starting for Cincinnati and at least one SportsLine analyst taking the points with the Bengals.
• Bookmakers detail sharp positions across the board — including Chiefs -1.5 and Lions–Chiefs Over 51/51.5 — and note a tracked $339,000 wager on Giants +7.5 at Caesars that cashed.