Overview

• Two elite receivers, Malik Nabers (ACL) and Tyreek Hill (knee dislocation), are out for the season, with James Conner also lost for the year and Cardinals rookie Trey Benson placed on injured reserve.
• Brock Purdy has been ruled out for Week 5, Lamar Jackson is listed as doubtful, and with J.J. McCarthy missing practice Carson Wentz is expected to start for Minnesota, tightening a QB market already thinned by byes.
• Rookie RB Woody Marks surged into Houston’s lead role after a 119-yard, two-TD breakout and is a top waiver add across formats.
• Darren Waller returned for Miami with two touchdowns and profiles as a primary pass-game beneficiary of Hill’s absence despite a limited practice tag this week.
• Kendre Miller’s workload is growing for the Saints with bench-stash RB2 upside, the Giants’ Darius Slayton gains targets with Jaxson Dart under center, and Arizona’s backfield tilts to Michael Carter by his own indication with Emari Demercado also in play.