Overview

• Season-ending losses to James Conner and Najee Harris are confirmed, elevating Trey Benson to Arizona’s lead role and securing rookie Omarion Hampton as the Chargers’ primary back, with Emari Demercado and Hassan Haskins in supporting duties.
• CeeDee Lamb (ankle) and Mike Evans (hamstring) are expected to miss multiple weeks, with reports projecting roughly three to four weeks for each, reinforcing the need for short-term receiver pivots.
• Consensus Week 4 quarterback guidance highlights Lamar Jackson, Josh Allen, Jalen Hurts and Caleb Williams as the safest starts, with Washington’s spot still unsettled as Jayden Daniels rehabs a knee sprain and Marcus Mariota remains a viable streamer.
• Team decisions further shake depth charts: the Giants benched Russell Wilson for rookie Jaxson Dart, the Vikings plan to keep JJ McCarthy out until around Week 7, and Brock Purdy is trending toward a return while Justin Fields’ concussion status bears monitoring.
• Waiver and streaming tools point to immediate action, with one outlet’s drop list including Russell Wilson, Hollywood Brown, Dylan Sampson and Kaleb Johnson, and matchup calls flagging favorable spots such as Chargers receivers versus the Giants and Jordan Love at Dallas.