Week 10: Seahawks Host Cardinals on CBS With Seattle Favored by 6.5

With Kyler Murray on injured reserve, sportsbooks list Seattle as 6.5-point favorites over Arizona.

Overview

Kickoff is 4:05 p.m. ET at Lumen Field on CBS and Paramount+, with Kevin Harlan, Trent Green and Melanie Collins on the call.
Seattle is 6-2 and tied atop the NFC West after a 38-14 win at Washington, while Arizona is 3-5 after snapping a five-game skid with a 27-17 win at Dallas.
Jacoby Brissett remains Arizona’s starter after Murray’s foot injury landed him on IR, and Brissett has seven total touchdowns with fewer turnovers than Murray in fewer starts.
SportsLine consensus lists Seattle at -6.5 with a -209 money line and a 45.5 total, and the last six meetings in Seattle have gone under the number.
The SportsLine model projects Seahawks 26, Cardinals 17 with Seattle covering in 55% of simulations, and the Seahawks have won eight straight against Arizona, going 7-1 against the spread.