Particle.news

Download on the App Store

Wearable Bee-Sting-Inspired Microneedles Boost Drug Absorption in Preclinical Study

An electrospun fibrous web on metal tips anchors the patch to skin for continuous delivery without the irritation seen with rigid microneedles.

Overview

  • A Chung-Ang University team led by Professor Wonku Kang with Dr. Sohee Jeon and Dr. Jun-Ho Jeong developed Electrospun Web Microneedle patches for long-term transdermal delivery.
  • The peer-reviewed study was published online on July 31, 2025, in Advanced Healthcare Materials.
  • Electrospinning creates a nanoscale fiber web around the microneedle tips that mimics bee-stinger barbs to secure attachment and support sustained release.
  • In guinea pigs receiving rivastigmine, the patches released more than twice the drug and covered roughly five times the area compared with conventional approaches, with minimal discomfort and irritation that resolved after removal.
  • The researchers aim to expand use to additional chronic diseases and patient groups, with further development and human trials still ahead.