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Virtual Infection Cues Activate Early Immune Defense

Researchers in Switzerland have shown that mere perception of infection signs in virtual reality primes innate immune cells before any pathogen invades.

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Overview

  • The study exposed 248 healthy adults to virtual avatars exhibiting symptoms like coughing or rash while recording EEG, fMRI and blood samples.
  • Participants exhibited elevated activity of innate lymphoid cells upon encountering ‘sick’ avatars, signaling preemptive immune mobilization.
  • EEG and fMRI measurements revealed increased engagement of brain regions involved in sensory integration and peripersonal space monitoring.
  • Subjects showed heightened facial touch sensitivity when avatars perceived as infectious entered their peripersonal space.
  • Researchers report that this VR-induced immune activation mirrors responses to influenza vaccination and emphasize the need for further exploration of neural-immune interactions.