Overview

• Jordan Addison, the Vikings' No. 2 wide receiver, will miss the Week 2 game against the 49ers due to an ankle injury.
• Safety Harrison Smith, right tackle Brian O'Neill, and right guard Ed Ingram are listed as questionable for the game.
• Jalen Nailor is expected to step up in Addison's absence, with Brandon Powell, Trent Sherfield, and Trishton Jackson also in the mix.
• Addison's absence follows an impressive rookie season and a strong performance in Week 7 against the 49ers last year.
• The Vikings are 5.5-point underdogs against the 49ers, who will test Minnesota's injury-hit offensive line with their formidable defense.