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Vigo Hospital Administers Spain’s First Public Gene Therapy for Hemophilia B

The one-time 2.8 million-euro Hemgenix infusion is financed through a risk-sharing structure designed to serve eight eligible patients in Galicia

Carmen Albo López, jefa del servicio de Hematología del hospital Álvaro Cunqueiro de Vigo.
Profesionales de Hematología y Farmacia del Chuvi, que administraron el fármaco, cn el gerente del área.
Momento de la administración de la terapia génica contra la hepatitis B en el hospital Álvaro Cunqueiro de Vigo.
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Overview

  • Hospital Álvaro Cunqueiro treated a man in his 40s with severe Hemophilia B on June 18, marking the first public-hospital use of Hemgenix in Spain
  • Etranacogen dezaparvovec delivers a functional copy of the factor IX gene to liver cells via a modified viral vector, enabling continuous production of the clotting protein
  • Xunta de Galicia invested 15.6 million euros to secure the therapy, with payments spread over five years and contingent on clinical outcomes
  • Access is restricted to adult patients without factor IX inhibitors who have undergone at least two years of extended half-life prophylaxis
  • Sergas anticipates that up to eight patients in Galicia will meet the stringent criteria to receive this functional cure therapy