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Vertex CEO Reshma Kewalramani Debuts at No. 62 on Fortune’s Most Powerful People in Business

Her debut on Fortune’s list recognizes her leadership at Vertex as CEO, reflecting the impact of the company’s newly approved opioid-free pain therapy

Overview

  • Reshma Kewalramani becomes the first woman to lead a major US biotechnology firm and debuts at number 62 on Fortune’s 2025 list of the 100 Most Powerful People in Business.
  • Fortune’s profile credits her with steering Vertex to FDA approval for Journavx, an opioid-free pain medication.
  • Kewalramani joined Vertex in 2017, was named chief medical officer in 2018 and has served as CEO and board member since April 2020.
  • Born in Mumbai and raised in the United States from age 11, she leverages her physician training to drive Vertex’s research and development strategies.
  • Her inclusion alongside leaders such as Sundar Pichai and Mukesh Ambani reflects increasing diversity at the top of global corporations.