Overview

• Williams lost to No. 11 seed Karolina Muchova 6-3, 2-6, 6-1 in roughly two hours and left Arthur Ashe to warm applause.
• Muchova, a past French Open finalist and recent US Open semifinalist, will face the winner of Sorana Cirstea vs. Solana Sierra, with Cirstea arriving as the Cleveland champion.
• Competing on a wild card and ranked No. 597, Williams made her 25th US Open singles appearance.
• No. 5 seed Mirra Andreeva, 18, advanced in 55 minutes with a 6-0, 6-1 win over Alycia Parks.
• Elsewhere, Petra Kvitova retired from professional tennis after a first-round defeat to Diane Parry, closing a 19-year career with 31 singles titles.