Overview
- Peer-reviewed results in European Urology Oncology report an international randomized trial of 212 men on active surveillance over four months.
- All participants took a phytochemical-rich supplement made from broccoli, turmeric, pomegranate, green tea, ginger and cranberry, with half also receiving a Lactobacillus probiotic.
- PSA levels fell more in the probiotic group, with a 44.6% reduction compared with a 13.1% drop for the supplement alone, indicating slower biomarker progression.
- MRI findings corroborated the PSA changes, with 82% stable disease on supplement plus placebo versus 85.5% stable, 6.7% regression and 7.8% progression on supplement plus probiotic.
- Researchers noted quality-of-life benefits including improved urinary symptoms in about one quarter of men and emphasized the need for larger, longer trials before clinical adoption.