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Vall d’Hebron Performs World’s First Face Transplant From Euthanasia Donor

Advance consent under Spain’s euthanasia law made meticulous 3D planning possible.

Overview

  • The Barcelona hospital disclosed the case on February 2 after months of follow-up, describing it as a global first in facial transplantation.
  • The recipient, Carme, received a central partial facial graft after severe necrosis from a 2024 insect‑bite infection left her unable to eat or speak.
  • About 100 specialists carried out the day‑long procedure to transplant skin, muscle, nerves and bone, with the team also reporting novel perfusion and neurophysiological monitoring.
  • Prearranged consent let clinicians obtain CT scans of donor and recipient, build 3D models and custom cutting guides, and coordinate the facial graft with multiorgan procurement.
  • Hospital officials say Carme can now swallow and speak and is in rehabilitation, and they note the donor’s lungs, liver, kidneys and tissues benefited multiple patients under strict anonymity rules.