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Vaccination Reduces Dialysis and Death Risk for COVID-19 Patients with Acute Kidney Injury

These results inform CDC’s upcoming vaccine advisory meetings on updated COVID-19 immunization guidelines later this month

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A person receives a Covid-19 vaccine in Valencia, Spain in 2023.
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Overview

  • The retrospective analysis included roughly 3,500 patients hospitalized with COVID-19 between March 2020 and March 2022.
  • Of the 972 patients who developed acute kidney injury, 467 had received at least two mRNA doses or a Johnson & Johnson vaccine.
  • Unvaccinated patients were 2.56 times more likely to need continuous renal replacement therapy after discharge compared with vaccinated patients.
  • Vaccination was linked to a 5.54-fold lower risk of in-hospital death and a 4.78-fold lower risk of mortality during long-term follow-up.
  • Researchers cited missing baseline creatinine data and lack of COVID-19 severity metrics as limitations and urged further investigation into post-COVID kidney outcomes.