Overview
- A peer‑reviewed synthesis in the Journal of Pharmaceutical Analysis (Bordin et al., 2025; DOI:10.1016/j.jpha.2025.101473) consolidates advances and applications for monitoring hormones, medications and early disease signals using sweat.
- Progress in microfluidics, stretchable electronics and low‑power wireless has enabled thin skin‑adherent patches that continuously sample sweat, though most platforms remain at the prototype stage.
- Artificial intelligence is expected to interpret complex biochemical patterns in sweat, with the next milestone being integration into compact, secure, low‑power devices rather than reliance on bench‑top analysis.
- UTS teams are mapping baseline sweat physiology and developing microfluidic sensors capable of detecting trace biomarkers such as glucose and cortisol.
- Clinical translation requires standardized collection, normalization and validation, plus quantitative sweat–blood correlations and robust signal processing, as echoed by a concurrent arXiv review focused on biosensing mechanisms and electronics.