Overview

• Kickoff is Saturday at 11 p.m. ET (8 p.m. PT) at the Los Angeles Memorial Coliseum on FOX.
• Both teams are 3-0, with No. 25 USC opening Big Ten play last week and Michigan State beginning conference play on the road.
• Michigan State’s top receiver Nick Marsh and starting running back Makhi Frazier remain questionable with leg injuries, per coach Jonathan Smith.
• USC quarterback Jayden Maiava leads the Big Ten in passing yards through three games, and the Trojans’ defense leads the nation with 14 sacks.
• Oddsmakers list USC as roughly an 18.5‑point favorite for a matchup billed as a ‘Big Ten After Dark’ test following Michigan State’s early arrival to acclimate.