Overview
- The game kicks off at 4:30 p.m. PT on Saturday, Sept. 26 at the Los Angeles Memorial Coliseum and will air on NBC with streaming options on Fubo and Peacock.
- Betting markets opened with Oregon as roughly a 3-point favorite and an over/under in the low 60s, reflecting expectations for a high-scoring matchup.
- USC defensive lineman Jahkeem Stewart is listed as questionable and his Instagram post and team comments suggest he is trending toward playing, while Oregon tight end Jamari Johnson is also questionable and is expected to be a game‑time decision.
- The game is framed as especially consequential for USC coach Lincoln Riley, whose fifth season has lacked consistent signature wins, and a loss would intensify scrutiny of the program’s national trajectory.
- Both teams bring explosive offenses and vulnerable defenses to the Coliseum: Oregon averages about 49.7 points per game and USC’s Jayden Maiava leads the Big Ten in passing production, setting up a battle where available playmakers and health will likely decide the result.