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US-Iran Nuclear Talks Progress with Second Meeting Set for Rome

Following constructive discussions in Oman, the US and Iran prepare for further negotiations on April 19, focusing on limiting Iran's nuclear program in exchange for sanctions relief.

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Infographic with a map of Iran showing nuclear sites, reactors and uranium mines.
A general view of Muscat, during negotiations between U.S. and Iran, in Oman, April 12, 2025. REUTERS/Mohammed Mahjoub/File Photo

Overview

  • The first high-level US-Iran nuclear talks since 2018 took place on April 12 in Oman, described by both sides as positive and constructive.
  • A second round of negotiations is scheduled for April 19 in Rome, with the aim of advancing discussions on limiting Iran's nuclear activities.
  • Iran seeks sanctions relief to address severe economic challenges, while the US demands assurances that Iran will not develop nuclear weapons.
  • President Trump reiterated the US red line against Iranian nuclear armament and warned of potential military action if diplomacy fails.
  • The International Atomic Energy Agency (IAEA) is set to visit Tehran on April 16 to address unresolved issues related to Iran's uranium enrichment activities.