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US FDA Clears Lupin’s Armlupeg, a Neulasta Biosimilar, for U.S. Use

The approval opens access to a $1.295 billion pegfilgrastim syringe market in the United States, according to IQVIA.

Overview

  • Armlupeg (pegfilgrastim-unne) 6 mg/0.6 mL is approved as a single-dose prefilled syringe for subcutaneous use.
  • The product will be manufactured at Lupin’s biotech facility in Pune, which the FDA inspected before approval.
  • Indications include reducing febrile neutropenia in patients with non-myeloid cancers receiving myelosuppressive therapy.
  • The drug is also cleared to increase survival after acute exposure to myelosuppressive levels of radiation.
  • CEO Vinita Gupta cast the decision as a step toward a broader U.S. biosimilars portfolio, with modest share moves reported following the announcement.