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U.S. Drug Overdose Deaths Reach Record High in 2022, CDC Reports

Nearly 108,000 Americans lost their lives to drug overdoses last year, with fentanyl driving the surge.

  • Drug overdose deaths in the U.S. hit a new record in 2022, with 107,941 fatalities reported.
  • Fentanyl and other synthetic opioids continue to fuel the rise in overdose deaths, with deaths involving cocaine and methamphetamine also increasing.
  • The overdose death rate among men rose, while it declined for women for the first time in five years.
  • American Indian and Alaska Native populations saw the largest increase in overdose death rates.
  • Efforts to combat the crisis include the deployment of anti-overdose devices and overdose prevention centers.
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