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U.S. and Iran Set to Resume Nuclear Talks in Oman as Technical Discussions Advance

Following progress in Rome, expert-level talks and a third high-level meeting aim to address key disputes over uranium enrichment and sanctions relief.

The frontpages of Iran's newspapers in a sidewalk newsstand in Tehran, Iran on April 13, 2025 show a widespread optimism in Iran towards the nuclear talks with the administration of US President Donald Trump, one day after the first leg of the talks were held in Oman.
A mural depicting two officials sitting across a table is seen painted on the outer walls of the former U.S. embassy in Tehran on April 19, 2025 in Tehran, Iran. Talks between the United States and Iran over the fate of the Islamic Republic's uranium enrichment program continue at the Omani embassy in Rome. (Photo by Majid Saeedi/Getty Images)
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Iranian Foreign Minister Abbas Araghchi gives a briefing on the sidelines of a UN event in Lisbon, Portugal, November 27, 2024. REUTERS/Pedro Nunes

Overview

  • The U.S. and Iran will hold a third round of high-level nuclear negotiations in Muscat, Oman, later this week, following recent talks in Rome described as making 'very good progress.'
  • Expert-level technical discussions, initially planned for Wednesday, have been rescheduled to Saturday to align with the high-level meeting.
  • Both sides have agreed to begin drafting a framework for a potential deal, though differences remain over Iran’s uranium enrichment levels and the scope of economic sanctions relief.
  • Iran, under severe international sanctions, insists its nuclear program is peaceful and has expressed willingness to consider limited curbs in exchange for significant sanctions relief.
  • Experts caution that while advancing to technical talks is a positive step, it does not guarantee an imminent agreement, as key political and technical hurdles remain unresolved.