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U.S. Airstrike on Yemen’s Ras Isa Port Kills 74 in Deadliest Campaign Attack

The April 17 strike targeted Houthi-controlled fuel infrastructure to cut off revenue, with retaliation escalating regional tensions.

Fire and smoke rise next to charred vehicles following, what Al Masirah TV said, was a U.S. strike on the Ras Isa fuel port, Yemen, in this screengrab from a handout video released on April 18, 2025. Al-Masirah TV /Handout via REUTERS    THIS IMAGE HAS BEEN SUPPLIED BY A THIRD PARTY. NO RESALES. NO ARCHIVES
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Overview

  • The U.S. strike on Ras Isa fuel terminal killed at least 74 people and injured 171, according to Houthi health authorities, marking the deadliest attack in the campaign so far.
  • The U.S. Central Command stated the objective was to degrade Houthi fuel revenues, which fund their military operations and regional destabilization efforts.
  • The Houthis retaliated by launching a missile toward Israel, which was intercepted by Israeli defenses, further heightening regional tensions.
  • The Ras Isa terminal, a critical economic hub with a capacity of three million barrels, suffered extensive damage, with reports of oil leaking into the Red Sea.
  • The Houthi-controlled Health Ministry reported that workers and rescue teams were among the casualties, accusing the U.S. of targeting civilian infrastructure.