Overview
- President Claudia Sheinbaum condemned the assassination, ruled out a return to a militarized drug war, and promised justice, drawing criticism for blaming past administrations and castigating the press.
 - Columnists report the case has triggered the first major internal crisis for the federal security cabinet after a faltering damage‑control effort.
 - Manzo had warned on October 8 that 200 National Guard personnel left Uruapan, and media citing federal sources say he was under a 14–16 person guard when a lone 19‑year‑old attacker killed him at close range.
 - Public anger in Michoacán has intensified with demonstrations urging Governor Alfredo Ramírez Bedolla to resign, as seven mayors have been killed nationwide this year, including three in the state.
 - U.S. outlets report Washington has begun planning operations against designated trafficking groups in Mexico, and analysts warn that insecurity and impunity are eroding investor confidence.