Overview
- Cornerback Upton Stout moved into a blue non‑contact/limited role at Thursday’s practice and is considered a possible option for Sunday’s game at Lumen Field.
- Defensive lineman Mykel Williams continued his comeback from a 2025 ACL tear and is expected to be activated for the Week 5 game, with the team opening a roster spot after releasing Ogbo Okoronkwo.
- All‑Pro Nick Bosa did not practice and is not expected to return this week because of a lingering calf issue, and full‑time starters James Thompson Jr. and Kyle Juszczyk also missed practices.
- Safety Marques Sigle is projected to miss multiple weeks with a high‑ankle sprain and Malik Mustapha is lined up to take his snaps in the short term.
- Wide receiver Mike Evans was kept on the side early in the week but returned in uniform on Friday as the 49ers manage a rib issue, a pattern that underscores how the team is balancing near‑term availability with longer‑term health during a key 4‑0 stretch against the defending champions.