Unranked Nebraska, Iowa State Upset No. 1 Purdue, No. 2 Houston
Purdue's loss marks fourth upset by unranked team in two seasons, Houston suffers first loss of the season
- Nebraska and Iowa State, both unranked, defeated No. 1 Purdue and No. 2 Houston respectively in upsets.
- Nebraska's victory over Purdue marked their first win over a top-ranked team since 1982.
- Purdue's loss to Nebraska is the fourth time in the past two seasons that a No. 1-ranked Purdue team has lost to an unranked opponent.
- Houston's loss to Iowa State was their first loss of the season, making them the last team in men's college basketball to lose a game this season.
- The losses by Purdue and Houston open the door for No. 3 Kansas to return to No. 1.