Overview
- Goals from Lucas Assadi in the fifth minute and Javier Altamirano early in the second half delivered a 2-1 second‑leg win that sent Universidad de Chile through.
- Universidad de Chile will face Lanús in the semifinals, opening at Francisco Sánchez Rumoroso on October 22 before the return at Néstor Díaz Pérez on October 29.
- Independiente del Valle advanced to meet Atlético Mineiro after a 2-0 win in regulation and a 5-4 penalty shootout over Once Caldas.
- The other semifinal opens October 22 in Quito and concludes October 29 at Arena MRV in Belo Horizonte, with all matches on ESPN/Disney platforms.
- Alianza Lima now pivots to domestic play with an away match at Cienciano on September 28, as Pablo Ceppelini expressed pride but lamented errors and the first‑leg red card that weighed on the tie.