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Underground Mosquito Didn’t Emerge in London—It Originated Millennia Ago in the Mediterranean

Genomic comparisons with historic museum DNA point to a MediterraneanMiddle East divergence thousands of years ago.

Overview

  • A Science study dated Oct. 23 finds Culex pipiens f. molestus split from bird-biting pipiens roughly 1,300–12,500 years ago in the Mediterranean or Middle East, overturning the London Underground origin story.
  • Researchers analyzed whole genomes from 357 mosquitoes collected at 77 sites across western Eurasia, supported by DNA from historic Natural History Museum specimens in London.
  • Evidence suggests early agricultural irrigation and stored water provided year‑round breeding sites that fostered human-associated traits long before modern subways existed.
  • Molestus shows adaptations for subterranean life—biting mammals, mating in confined spaces, staying active in winter, and laying eggs without a blood meal—traits that later thrived in urban belowground habitats.
  • Hybridization with pipiens appears less common than assumed but occurs in large cities, prompting calls for targeted sampling to clarify gene flow, biting behavior, and West Nile virus spillover risk.