Ultrasound Technology Enhances Alzheimer's Drug Delivery in New Study

Focused ultrasound temporarily breaches blood-brain barrier, allowing for faster and more efficient drug seepage into the brain.

Scientists have found a way to help Alzheimer’s drugs seep inside the brain faster by temporarily breaching its protective shield, the blood-brain barrier.
The technology used is called focused ultrasound, which creates temporary openings in the blood-brain barrier, allowing medications to slip in.
The study involved three patients with mild Alzheimer's who were given monthly doses of an Alzheimer's drug, Aduhelm, for six months.
Post-treatment PET scans showed about 32% greater plaque reduction in spots where the blood-brain barrier was breached compared to the same region on the brain’s opposite side.
The study is seen as a promising proof-of-concept, but larger studies are needed to confirm the effectiveness of this approach.