Particle.news
Download on the App Store

Ultrasound Study Presented at RSNA Maps Filler-Related Vascular Blockages

Researchers report that targeting hyaluronidase at the occlusion site may improve precision, reducing enzyme use.

Overview

  • A multicenter series of 100 patients from May 2022 to April 2025, presented at RSNA 2025, found vascular ultrasound can pinpoint arterial occlusions caused by hyaluronic acid fillers.
  • Absent flow to perforator vessels was identified in 42% of cases, while 35% showed loss of flow in major vessels with a significant tie to the lateral nasal artery.
  • The nasal region was highlighted as particularly high risk due to vascular connections to facial and retinal circulation that can lead to blindness or stroke.
  • Ultrasound-guided hyaluronidase injections allow clinicians to target the precise blockage, use less enzyme, and report better treatment results.
  • Authors also promote ultrasound guidance during filler placement to improve accuracy and potentially reduce filler volume, while emphasizing that the findings are preliminary until peer-reviewed.