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Ultrasound Probe Maps Whole-Organ Blood Flow in 4D, Paving Path to Human Trials

Peer-reviewed results move a non-invasive, portable-compatible system toward first human trials.

Overview

  • Researchers at Inserm’s Physics for Medicine Institute report the first full-organ 4D blood-flow maps in large animal models of the heart, kidney and liver.
  • The approach uses multi-lens ultrasound arrays to resolve microvessels under 100 micrometers and to quantify flow dynamics across entire organs.
  • In the liver, the method distinguishes arterial, venous and portal networks based on their hemodynamic signatures.
  • Findings are published in Nature Communications, and the team released an illustrative video on October 28.
  • The non-invasive probe connects to small portable equipment, and Inserm’s Technological Research Accelerator is supporting preparations for human testing.