Overview

• Researchers at Northwestern Medicine used ultrasound to penetrate the blood-brain barrier, allowing drug delivery.
• The method combines low doses of chemotherapy and immunotherapy to boost immune system recognition of cancer cells.
• A clinical trial has been launched to evaluate the safety and effectiveness of the new approach in prolonging survival.
• Initial studies in both mice and humans indicate improved drug penetration and immune response against glioblastoma.
• This approach may overcome previous challenges in treating glioblastoma due to poor drug delivery to the brain.