Overview

• Ultrafine bubble showers significantly improved symptoms of allergen-induced atopic dermatitis in mice, reducing inflammation and enhancing skin barrier proteins.
• The treatment showed no significant benefits for genetically driven eczema, highlighting the need for personalized approaches to managing the condition.
• The study's short duration of 7-14 days and its focus on mice underscore the necessity of longer-term human trials to validate the findings.
• Ultrafine bubbles, already used in medical equipment cleaning, could offer a non-invasive, drug-free option for managing certain eczema cases if proven effective in humans.
• The research was funded by Osaka city and Science Co., Ltd., raising potential conflict-of-interest concerns as one study author is employed by the company.