Overview
- Genomic sequencing identified a hybrid mpox genome containing elements of clade Ib and clade IIb, indicating recombination of currently circulating lineages.
- The case was detected in an individual with recent travel to Asia, and the UKHSA has notified the World Health Organization as analysis continues.
- Experts say recombination was anticipated with co-circulating strains, but any changes in transmissibility, severity or test detection remain under evaluation.
- UKHSA reiterated the targeted vaccination offer for higher‑risk groups, citing research that suggests about 75%–80% protection against mpox.
- Health guidance highlights common symptoms such as fever and a blistering rash, notes transmission through close contact, and advises suspected cases to contact NHS 111 or sexual health services.