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UKHSA Detects Recombinant Mpox Strain in England Linked to Travel From Asia

Officials are assessing whether the recombinant changes disease behaviour.

Overview

  • Genomic sequencing showed the virus contains elements of clade Ib and IIb, confirming a recombinant genome.
  • UKHSA has informed the World Health Organization and other partners and is investigating the strain’s significance.
  • Experts said recombination was expected with ongoing global circulation, with any impact on transmissibility or severity still unknown.
  • Eligible groups are urged to get vaccinated, with studies indicating roughly 75–80% protection against mpox.
  • Transmission occurs through close physical contact, and symptoms typically begin with flu-like illness followed by a blistering rash.