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UKHSA Detects Recombinant Mpox Strain in England

Officials are evaluating its potential impact.

Overview

  • Genomic sequencing identified the virus in an individual who had recently returned from Asia.
  • Testing shows the genome contains elements of mpox clades Ib and IIb, reflecting recombination when multiple clades co-circulate.
  • UKHSA has notified the World Health Organization to support international surveillance.
  • There is no evidence yet of altered severity or transmission, and eligible people are being urged to get vaccinated.
  • The NHS vaccination programme focuses on higher-risk groups, with studies estimating 75–80% effectiveness, and officials reiterate the 5–21 day incubation and symptoms such as fever and a rash.