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UK Reports Spotlight Trial Showing Curcumin Matches Omeprazole for Functional Dyspepsia

Clinicians urge caution given the small, brief trial with a liver-function signal in overweight participants.

Overview

  • Mirror, Birmingham Live and the Daily Record highlighted the findings after Dr Michael Ruscio told his YouTube audience curcumin could be "just as effective" as omeprazole for reflux and indigestion.
  • A 2023 multicentre, double-blind trial in BMJ Journals tested curcumin at 2 grams daily for one month and found symptom relief comparable to omeprazole for functional dyspepsia.
  • Researchers observed no major side effects overall, though overweight participants taking curcumin showed declines in liver function tests.
  • The authors described the evidence as reliable but limited by a small sample and short follow-up, calling for larger and longer studies before any practice changes.
  • Readers are advised to consult a GP before replacing prescribed PPIs, which are widely used in England and have reported long-term risks including nutrient malabsorption, bone and kidney problems, and higher infection susceptibility.