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UK Confirms Recombinant Mpox Case in Traveler From Asia

Authorities have begun genomic assessment to determine any change in behavior.

Overview

  • The case was identified in England in a recent traveler from Asia, and UKHSA has informed the WHO.
  • Sequencing shows a recombinant virus combining elements of clade I and clade II, with clade I linked to more severe illness.
  • Specialists warn of possible shifts in transmissibility, virulence, or test detection, though no such changes have been confirmed.
  • UKHSA urges eligible people to get vaccinated under the routine program, citing studies estimating roughly 75–80% protection.
  • Suspected cases are advised to contact NHS 111 for guidance, as surveillance continues given global co-circulation and recent reports of local spread in several countries.