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UK Confirms Genetically Distinct Mpox Case as Classification Under Review

UK health officials are analyzing the genome to resolve its classification.

Overview

  • UKHSA identified a single Mpox infection in England through genomic sequencing and described the virus as genetically distinct.
  • Official descriptions differ on the lineage, with one report linking it to clade Ib and another describing a recombinant Ib/IIb strain under evaluation.
  • Accounts also diverge on recent travel history, with one citing West Africa and another Asia, and the source is still being investigated.
  • The patient is in isolation, contacts are being traced, and no secondary cases have been reported so far.
  • UKHSA has shared findings with WHO, is reviewing vaccine implications, and continues to recommend vaccination for eligible groups with studies indicating 75–80% effectiveness.